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In order to overcome a unit-of-analysis error for trials that contributed multiple, correlated comparisons, we used two approaches: we combined all relevant experimental intervention groups of the trials into a single group and also combined all relevant control intervention groups into a single control group so we could create a single pair-wise comparison () when the objective was to compare the experimental branch with any other control group (e.

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Interferons are immune factors that are being used to treat a number of serious conditions.

It is believed that actinic keratosis develops in skin cells called “keratinocytes”, which are the cells that constitute about 90% of the epidermis, the outermost layer of skin.

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In addition to Guidelines specific indication and use, NCCN adds relevant information such as pharmacologic class, relevant ICD-9 and ICD-10 codes, and FDA indication to the searchable database.

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Between 30% and 50% of patients with nonmelanoma skin cancer will have their cancer return within 5 years.

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Imiquimod Cream was evaluated in two randomized, vehicle-controlled, double-blind trials involving 702 pediatric subjects with molluscum contagiosum (MC) (470 exposed to imiquimod; median age 5 years, range 2-12 years).

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These data show that persisting vaccine depots can induce specific T cell sequestration, dysfunction and deletion at vaccination sites; short-lived formulations may overcome these limitations and result in greater therapeutic efficacy of peptide-based cancer vaccines.

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Patients who had a partial response at the end of the 8-week treatment period were evaluated again at week 2 of follow-up to determine whether they had achieved complete clearing.

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Roflumilast: May enhance the immunosuppressive effect of Immunosuppressants.

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Because of the known effects of prostaglandin-inhibiting drugs on the fetal cardiovascular system (closure of the ductus arteriosus), use of diclofenac during late pregnancy should be avoided and, as with other nonsteroidal anti-inflammatory drugs, it is possible that diclofenac may inhibit uterine contractions and delay parturition.

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Imiquimod is an immunomodulating drug, that has been reported to be effective in human papilloma virus-related disease, such as vulvar intraepithelial neoplasia (VIN), vaginal intraepithelial neoplasia (VAIN), and anal intraepithelial neoplasia (AIN).

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Many cutaneous changes seen in the renal transplant recipient (RTR) are related directly to medications used to suppress rejection of renal allograft.

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You and your healthcare provider should decide if you will use Diclofenac Sodium Gel or breastfeed.

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