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In order to overcome a unit-of-analysis error for trials that contributed multiple, correlated comparisons, we used two approaches: we combined all relevant experimental intervention groups of the trials into a single group and also combined all relevant control intervention groups into a single control group so we could create a single pair-wise comparison () when the objective was to compare the experimental branch with any other control group (e.

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Interferons are immune factors that are being used to treat a number of serious conditions.

It is believed that actinic keratosis develops in skin cells called “keratinocytes”, which are the cells that constitute about 90% of the epidermis, the outermost layer of skin.

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In addition to Guidelines specific indication and use, NCCN adds relevant information such as pharmacologic class, relevant ICD-9 and ICD-10 codes, and FDA indication to the searchable database.

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Between 30% and 50% of patients with nonmelanoma skin cancer will have their cancer return within 5 years.

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Imiquimod Cream was evaluated in two randomized, vehicle-controlled, double-blind trials involving 702 pediatric subjects with molluscum contagiosum (MC) (470 exposed to imiquimod; median age 5 years, range 2-12 years).

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These data show that persisting vaccine depots can induce specific T cell sequestration, dysfunction and deletion at vaccination sites; short-lived formulations may overcome these limitations and result in greater therapeutic efficacy of peptide-based cancer vaccines.

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Patients who had a partial response at the end of the 8-week treatment period were evaluated again at week 2 of follow-up to determine whether they had achieved complete clearing.

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Roflumilast: May enhance the immunosuppressive effect of Immunosuppressants.

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Because of the known effects of prostaglandin-inhibiting drugs on the fetal cardiovascular system (closure of the ductus arteriosus), use of diclofenac during late pregnancy should be avoided and, as with other nonsteroidal anti-inflammatory drugs, it is possible that diclofenac may inhibit uterine contractions and delay parturition.

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Imiquimod is an immunomodulating drug, that has been reported to be effective in human papilloma virus-related disease, such as vulvar intraepithelial neoplasia (VIN), vaginal intraepithelial neoplasia (VAIN), and anal intraepithelial neoplasia (AIN).

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Many cutaneous changes seen in the renal transplant recipient (RTR) are related directly to medications used to suppress rejection of renal allograft.

Activity ex vivo of cytotoxic drugs in patient samples of peritoneal carcinomatosis with special focus on colorectal cancer.

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You and your healthcare provider should decide if you will use Diclofenac Sodium Gel or breastfeed.

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